You are correct, the problem is not caused by https inspection. Possible causes of timeout: Intrusion Protection Service blocks the reply packet. If this happens, it should be in the IPS log file. Upstream firewall blocks either the request or the reply packets. This is only possible if you have another firewall. Routing problem causes the request or the reply packets to be lost. DNS lookup failure causes the destination to be unknown. Wiring problem causes excessive retransmits on the Ethernet, particularly having one device set to fixed speed and duplex while the other device is set to auto speed and duplex. I cannot think of any others.
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